The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 13, 2023

Filed:

Apr. 04, 2018
Applicants:

Quan Qing, Chandler, AZ (US);

Yuan Wang, Anhui, CN;

Joshua Sadar, Gilbert, AZ (US);

Inventors:

Quan Qing, Chandler, AZ (US);

Yuan Wang, Anhui, CN;

Joshua Sadar, Gilbert, AZ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); C12Q 1/6869 (2018.01); G01N 27/327 (2006.01); B82Y 15/00 (2011.01); G01N 33/487 (2006.01);
U.S. Cl.
CPC ...
B01L 3/5027 (2013.01); B01L 3/502707 (2013.01); B01L 3/502761 (2013.01); C12Q 1/6869 (2013.01); G01N 27/3276 (2013.01); G01N 27/3278 (2013.01); B01L 2300/0645 (2013.01); B01L 2300/0896 (2013.01); B82Y 15/00 (2013.01); G01N 33/48721 (2013.01);
Abstract

The present disclosure provides chips, devices and methods for sequencing a biomolecule. The biomolecule may be DNA, RNA. a protein, or a peptide. The chip comprises a substrate; a first and second fluid chamber; fluid channels connecting the first and second fluid chamber; a first and second electrode disposed on opposing sides of the central fluid channel and having a nanogap therebetween, wherein the width of the nanogap is modulated by confined electrochemical deposition; and a passivation layer disposed on top of the first and second electrodes and the fluid channel.


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