The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 13, 2023
Filed:
Dec. 18, 2020
The Hospital for Sick Children, Toronto, CA;
The Royal Institution for the Advancement of Learning/mcgill University, Montreal, CA;
Lynne P. Howell, Toronto, CA;
Perrin Baker, Mississauga, CA;
Noor Alnabelseya, San Francisco, CA (US);
Natalie Bamford, Toronto, CA;
Dustin Little, Burlington, CA;
Donald Sheppard, Montreal, CA;
Brendan Snarr, North Bethesda, MD (US);
Mark Jae Lee, Burbank, CA (US);
The Hospital for Sick Children, Toronto, CA;
The Royal Institution for the Advancement of Learning/McGill University, Montreal, CA;
Abstract
The present disclosure relates to methods of treating or preventing a biofilm-related infection and methods of preventing and treating biofilm formation on indwelling medical devices, implants, and non-medical surfaces comprising administering at least one soluble microbial protein that is encoded by an exopolysaccharide biosynthetic operon or functional gene cluster, wherein the protein comprises a glycosyl hydrolase domain. The present disclosure further provides particular soluble glycosyl hydrolases and compositions thereof.