The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 13, 2023
Filed:
Oct. 30, 2020
Applicant:
Stealth Biotherapeutics Inc., Needham, MA (US);
Inventor:
D. Travis Wilson, Newton, MA (US);
Assignee:
STEALTH BIOTHERAPEUTICS INC., Needham, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 38/18 (2006.01); A61K 38/19 (2006.01); A61K 38/17 (2006.01); C07K 14/475 (2006.01); C07K 14/48 (2006.01); C07K 5/00 (2006.01); C07K 7/00 (2006.01); A61K 38/07 (2006.01); A61K 45/06 (2006.01); A61K 38/28 (2006.01); A61K 31/122 (2006.01); A61K 31/401 (2006.01); A61K 31/4412 (2006.01); A61K 31/7048 (2006.01); C07K 5/11 (2006.01); A61P 43/00 (2006.01); A61P 21/00 (2006.01); A61Q 19/08 (2006.01); G01N 33/68 (2006.01); C07K 5/10 (2006.01); A61K 9/50 (2006.01); A61P 25/28 (2006.01);
U.S. Cl.
CPC ...
A61K 38/07 (2013.01); A61K 31/122 (2013.01); A61K 31/401 (2013.01); A61K 31/4412 (2013.01); A61K 31/7048 (2013.01); A61K 38/28 (2013.01); A61K 45/06 (2013.01); C07K 5/1019 (2013.01); A61K 9/5052 (2013.01); A61K 2300/00 (2013.01); A61P 21/00 (2018.01); A61P 25/28 (2018.01); A61P 43/00 (2018.01); A61Q 19/08 (2013.01); C07K 5/10 (2013.01); G01N 33/68 (2013.01); G01N 2800/2835 (2013.01);
Abstract
The disclosure provides methods of preventing or treating Friedreich's ataxia in a mammalian subject, reducing risk factors, signs and/or symptoms associated with Friedreich's ataxia, and/or reducing the likelihood or severity of Friedreich's ataxia. The methods comprise administering to the subject an effective amount of an aromatic-cationic peptide to e.g., reduce oxidative stress, increase mitochondrial metabolism, or a combination thereof.