The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 13, 2023
Filed:
Apr. 08, 2021
Applicant:
City of Hope, Duarte, CA (US);
Inventors:
Binghui Shen, Duarte, CA (US);
Li Zheng, Duarte, CA (US);
Karen Reckamp, Duarte, CA (US);
Ravi Salgia, Duarte, CA (US);
Assignee:
CITY OF HOPE, Duarte, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/665 (2006.01); A61K 31/517 (2006.01); A61P 35/00 (2006.01); A61K 31/506 (2006.01); A61K 31/585 (2006.01); A61K 31/5377 (2006.01);
U.S. Cl.
CPC ...
A61K 31/665 (2013.01); A61K 31/506 (2013.01); A61K 31/517 (2013.01); A61K 31/5377 (2013.01); A61K 31/585 (2013.01); A61P 35/00 (2018.01);
Abstract
Provided herein, inter alia, are methods, compositions and kits for treating cancer in a subject. The methods include administration of one or more tyrosine kinase inhibitors and triptolide or an analog thereof to the subject. The methods, compositions and kits are effective for preventing resistance and/or increasing sensitivity to tyrosine kinase inhibitors.