The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 13, 2023
Filed:
Jul. 17, 2020
Applicant:
Northwestern University, Evanston, IL (US);
Inventors:
Lu Wang, Chicago, IL (US);
Ali Shilatifard, Chicago, IL (US);
Assignee:
NORTHWESTERN UNIVERSITY, Evanston, IL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/473 (2006.01); A61P 35/02 (2006.01); A61K 31/423 (2006.01);
U.S. Cl.
CPC ...
A61K 31/473 (2013.01); A61K 31/423 (2013.01); A61P 35/02 (2018.01);
Abstract
Disclosed are methods for methods, compounds, and compositions for treating cancers characterized by therapeutic targeting of the BAP1 histone H2A deubiquitinase (DUB) complex, otherwise referred to herein as the BAP1 complex. In particular, the methods, compounds, and compositions disclosed herein relate to the use of therapeutic agents that inhibit the biological activity of the BAP1 complex for treating cancers such as myeloid neoplasms.