The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 06, 2023
Filed:
Jun. 12, 2018
Firalis SA, Huningue, FR;
Luxembourg Institute of Health, Luxembourg, LU;
The University Hospital of Lausanne, Lausanne, CH;
The Cardinal Stefan Wyszynski Institute of Cardiology, Warsaw, PL;
Hueseyin Firat, Huningue, FR;
Sabrina Danilin, Riedisheim, FR;
Yvan Devaux, Zoufftgen, FR;
Lu Zhang, Metz, FR;
Przemyslaw Leszek, Warsaw, PL;
Eric Schordan, Wentzwiller, FR;
Samir Ounzain, Lausanne, CH;
Thierry Pedrazzini, Lausanne, CH;
FIRALIS SA, Huningue, FR;
LUXEMBOURG INSTITUTE OF HEALTH, Luxembourg, LU;
THE UNIVERSITY HOSPITAL OF LAUSANNE, Lausanne, CH;
THE CARDINAL STEFA WUSZYNSKI INSTITUTE OF CARDIOLOGY, Warsaw, PL;
Abstract
The present invention provides methods for the diagnosing, monitoring and prognostication of primary and secondary cardiac disorders in a subject based on lncRNA expression. The invention also provides methods for predicting heart failure after myocardial infarction, and differenciation of Ischemic versus non-ischemic Heart Failure. The assessment/quantification of these lncRNAs may also be used as a marker for monitoring drug-induced cardiac toxicities and for the assessment of cardiac involvement during systemic diseases and others disorders/toxicities impacting cardiac function. These lncRNAs are cardiac tissue enriched and may be involved in different cardiac pathophysiological events and represent a potential target for therapeutical approaches.