The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 06, 2023

Filed:

Sep. 08, 2017
Applicant:

Korea University Research and Business Foundation, Seoul, KR;

Inventors:

Jae Sang Hong, Seoul, KR;

Do Hoon Lee, Seoul, KR;

Yu Jin Jang, Seoul, KR;

Jong Hoon Kim, Seoul, KR;

Young Sik Lee, Seoul, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/02 (2006.01); C07H 21/04 (2006.01); C12N 15/113 (2010.01); A61P 1/16 (2006.01); A61K 35/28 (2015.01); A61K 35/407 (2015.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); A61K 35/28 (2013.01); A61K 35/407 (2013.01); A61P 1/16 (2018.01); C12N 2310/141 (2013.01);
Abstract

The present invention relates to a composition or cell therapeutic agent for preventing or treating liver fibrosis, containing an exosome or exosome-derived ribonucleic acid. The exosome or ribonucleic acid derived therefrom, of the present invention, has effects of inhibiting activities of hepatic stellate cells and Kupffer cells and reducing the expression of α-SMA and inhibits the progression of liver fibrosis by inhibiting the deposition of collagen, thereby being effectively usable as a cell therapeutic agent for the prevention or treatment of liver fibrosis.


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