The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 06, 2023
Filed:
Feb. 02, 2021
Applicant:
Biorestorative Therapies, Inc., Melville, NY (US);
Inventor:
Francisco Javier Silva, Melville, NY (US);
Assignee:
BIORESTORATIVE THERAPIES, INC., Melville, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/0775 (2010.01); C12N 5/077 (2010.01); A61K 35/28 (2015.01); C12N 15/85 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0667 (2013.01); A61K 35/28 (2013.01); C12N 5/0653 (2013.01); C12N 15/85 (2013.01); G01N 33/5073 (2013.01); C12N 2510/04 (2013.01); G01N 2500/10 (2013.01);
Abstract
An isolated human brown adipose tissue stem cell line. In one embodiment, the isolated human brown adipose tissue stem cell line expresses the markers CD9, SSEA4, CD44, CD90, CD166, CD73, but not CD14, CD34, CD45 or STRO-1. In another embodiment, the isolated human brown adipose tissue stem cell line expresses the genes UCP1, PPARGC1A, NRF1, FOXC2, CREB1, SIRT3, and WNT5A (REFX). In still another embodiment, the isolated human brown adipose tissue stem cell line is capable of differentiating into osteoblasts, chondrocytes, and adipocytes.