The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 06, 2023
Filed:
Dec. 13, 2019
Applicants:
Fuzhong Zhang, St. Louis, MO (US);
Christopher H. Bowen, St. Louis, MO (US);
Bin Dai, St. Louis, MO (US);
Inventors:
Fuzhong Zhang, St. Louis, MO (US);
Christopher H. Bowen, St. Louis, MO (US);
Bin Dai, St. Louis, MO (US);
Assignee:
Washington University, St. Louis, MO (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/00 (2006.01); C07K 14/435 (2006.01); D01D 5/06 (2006.01); D01D 1/02 (2006.01); B29C 48/05 (2019.01); D01F 4/02 (2006.01); C12N 1/20 (2006.01); C12N 15/70 (2006.01);
U.S. Cl.
CPC ...
C07K 14/43518 (2013.01); B29C 48/05 (2019.02); C12N 1/20 (2013.01); C12N 15/70 (2013.01); D01D 1/02 (2013.01); D01D 5/06 (2013.01); D01F 4/02 (2013.01); B29K 2089/00 (2013.01); B29K 2995/0088 (2013.01); C07K 2319/21 (2013.01);
Abstract
The present disclosure is directed to systems and methods for synthesizing a spidroin. In some embodiments, the methods comprise synthesizing a monomer in vivo in a heterologous host, the monomer comprising an N-terminus IntC domain and a C-terminus IntN domain, and post-translationally polymerizing the synthesized monomer via in vitro split-intein mediated polymerization.