The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 06, 2023

Filed:

Dec. 30, 2020
Applicants:

Bayer Aktiengesellschaft, Leverkusen, DE;

Bayer Pharma Aktiengesellschaft, Berlin, DE;

Inventors:

Donald Bierer, Haan, DE;

Ingo Flamme, Reichshof, DE;

Dmitry Zubov, Remscheid, DE;

Thomas Neubauer, Wuppertal, DE;

Adrian Tersteegen, Wuppertal, DE;

Cathleen Juhl, Hamburg, DE;

Marie Glatz, Wuppertal, DE;

Jan Dreher, Wuppertal, DE;

Simon Holton, Berlin, DE;

Carsten Terjung, Bochum, DE;

Lars Baumann, Wülfrath, DE;

Thorsten Poethko, Schwelm, DE;

Jiancheng Xiong, Wuhan, CN;

Yibo Qiu, Ann Arbor, MI (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 7/08 (2006.01); A61P 13/12 (2006.01); A61K 38/10 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07K 7/08 (2013.01); A61K 38/10 (2013.01); A61K 45/06 (2013.01); A61P 13/12 (2018.01);
Abstract

The present invention relates to novel Mannose-binding lectin (MBL)-associated serine protease (MASP) inhibitory compounds, as well as analogues and derivatives thereof, to processes for the preparation thereof, to the use thereof alone or in combinations for treatment and/or prevention of diseases and to the use thereof for production of medicaments for treatment and/or prevention of diseases, especially for treatment and/or prevention of renal and cardiovascular disorders and of ischemia reperfusion injuries.


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