The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 06, 2023
Filed:
Apr. 27, 2021
Applicant:
Roche Innovation Center Copenhagen A/s, Hørsholm, DK;
Inventors:
Dennis Jul Hansen, Farum, DK;
Erik Daa Funder, Hilleroed, DK;
Assignee:
Roche Innovation Center Copenhagen A/S, Horsholm, DK;
Primary Examiner:
Int. Cl.
CPC ...
C07H 1/02 (2006.01); C07H 19/213 (2006.01);
U.S. Cl.
CPC ...
C07H 1/02 (2013.01); C07H 19/213 (2013.01);
Abstract
The present invention relates to a method for preparing stereodefined phosphorothioate oligonucleotides, especially locked stereodefined phosphorothioate oligonucleotides with a high yield, using pyridinium acidic salts as a coupling activator.