The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 06, 2023
Filed:
Jul. 14, 2020
Shanghai Modern Pharmaceutical Engineering Research Center Co., Ltd., Shanghai, CN;
Shanghai Institute of Pharmaceutical Industry, Shanghai, CN;
Jun He, Shanghai, CN;
Zhefeng Wang, Shanghai, CN;
Yuezhu Zhao, Shanghai, CN;
Yani Yang, Shanghai, CN;
Qinghui Fu, Shanghai, CN;
Wei Bian, Shanghai, CN;
Yuan Zhao, Shanghai, CN;
Chen Ge, Shanghai, CN;
Yue Zhang, Shanghai, CN;
Bing Yi, Shanghai, CN;
Minghao Niu, Shanghai, CN;
Jiuhui Zhang, Shanghai, CN;
SHANGHAI MODERN PHARMACEUTICAL ENGINEERING RESEARCH CENTER CO., LTD., Shanghai, CN;
SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY, Shanghai, CN;
Abstract
A phenyl-containing compound, an intermediate thereof, a preparation method therefor and an application thereof. Provided is a compound represented by formula I or a pharmaceutically acceptable salt thereof, where R, R, R, Rand Rare independently hydrogen, C-Calkyl, C-Calkoxy or C(═O)OR; where Ris C-Calkyl; Ris (II), (III) or (IV); and Ris —OH, —NH, —NHCH, —N(CH)or Calkoxy. The compound has a low critical micelle concentration (CMC) and good dilution resistance and is capable of enclosing an insoluble drug to form a small-molecule micelle having a high drug loading capacity and good stability.