The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 06, 2023
Filed:
May. 08, 2019
The United States of America,as Represented BY the Secretary,department of Health and Human Services, Bethesda, MD (US);
The Regents of the University of California, Oakland, CA (US);
Bruce A. Shapiro, Gaithersburg, MD (US);
Paul J. Zakrevsky, Frederick, MD (US);
Luc Jaeger, Goleta, CA (US);
The United States of America,as represented by the Secretary, Department of Health and Human Services, Bethesda, MD (US);
The Regents of the University of California, Oakland, CA (US);
Abstract
Disclosed are nanostructures comprising a ribonucleic acid (RNA) scaffold comprising a hexameric tetrahedral core. The tetrahedral core may comprise four hexameric RNA nanorings linked together. Related pharmaceutical compositions, methods of modulating the expression of a target gene in a mammal, methods of treating or preventing a disease in a mammal, and methods of producing a hexameric tetrahedral RNA nanostructure are also disclosed.