The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 06, 2023
Filed:
Feb. 24, 2017
Applicant:
Ramot AT Tel-aviv University Ltd., Tel-Aviv, IL;
Inventors:
Ronit Satchi-Fainaro, Tel-Aviv, IL;
Evgeni Pisarevsky, Tel-Aviv, IL;
Anat Eldar-Boock, Tel-Aviv, IL;
Dikla Ben-Shushan, Tel-Aviv, IL;
Yana Epshtein, Tel-Aviv, IL;
Anna Scomparin, Tel-Aviv, IL;
Assignee:
Ramot at Tel-Aviv University Ltd., Tel-Aviv, IL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/65 (2017.01); A61K 9/51 (2006.01); A61P 35/00 (2006.01); A61K 47/64 (2017.01); A61K 47/59 (2017.01); A61P 35/04 (2006.01); A61K 31/4184 (2006.01); A61K 31/506 (2006.01); A61K 31/4745 (2006.01);
U.S. Cl.
CPC ...
A61K 47/65 (2017.08); A61K 9/5153 (2013.01); A61K 31/4184 (2013.01); A61K 31/506 (2013.01); A61K 47/59 (2017.08); A61K 47/645 (2017.08); A61P 35/00 (2018.01); A61P 35/04 (2018.01); A61K 31/4745 (2013.01); A61K 2300/00 (2013.01);
Abstract
Polymeric conjugates comprising a polymeric matrix having associated therewith an agent that down-regulates an activity or expression of a polypeptide associated with onset or progression of melanoma, and optionally and preferably, an additional agent that acts in synergy with said agent, are provided. Synthetic methodologies for preparing these conjugates and uses thereof in treating melanoma and other cancerous diseases are also provided.