The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 06, 2023
Filed:
Nov. 19, 2018
Applicant:
Genentech, Inc., South San Francisco, CA (US);
Inventors:
Thomas Pillow, San Francisco, CA (US);
Jack Sadowsky, Dublin, CA (US);
Leanna Staben, San Francisco, CA (US);
Steven Staben, San Francisco, CA (US);
Binqing Wei, Belmont, CA (US);
Ingrid Wertz, South San Francisco, CA (US);
Pragya Adhikari, Fremont, CA (US);
Nicole Blaquiere, San Francisco, CA (US);
Peter Dragovich, San Diego, CA (US);
Wayne Fairbrother, Burlingame, CA (US);
Assignee:
Genentech, Inc., South San Francisco, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/551 (2006.01); A61K 47/54 (2017.01); A61K 47/68 (2017.01); A61K 47/65 (2017.01); A61P 37/06 (2006.01); A61P 35/00 (2006.01); C07K 16/28 (2006.01); C07K 16/32 (2006.01); C12N 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/551 (2013.01); A61K 47/545 (2017.08); A61K 47/65 (2017.08); A61K 47/68 (2017.08); A61P 35/00 (2018.01); A61P 37/06 (2018.01); C07K 16/2827 (2013.01); C07K 16/32 (2013.01); C12N 9/93 (2013.01); C12Y 203/02007 (2013.01);
Abstract
The subject matter described herein is directed to antibody-PROTAC conjugates (PACs), to pharmaceutical compositions containing them, and to their use in treating diseases and conditions where targeted protein degradation is beneficial.