The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 06, 2023
Filed:
Sep. 24, 2020
Applicant:
George Mason University, Fairfax, VA (US);
Inventors:
Mikell Paige, Fairfax, VA (US);
Gregory Petruncio, Fairfax, VA (US);
Yun Michael Shim, Charlottesville, VA (US);
Assignee:
George Mason University, Fairfax, VA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 225/00 (2006.01); A61K 31/436 (2006.01); A61K 31/439 (2006.01); A61P 11/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/439 (2013.01); A61P 11/00 (2018.01);
Abstract
Tacrolimus is an immunosuppressant drug. The present disclosure provides an anti-fibrotic agent by transforming Tacrolimus, such that the anti-fibrotic agent is used for treating fibrosis. The anti-fibrotic agent is not immunosuppressant. In one embodiment, the present invention provides a method to transform Tacrolimus into an anti-fibrotic agent.