The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 06, 2023

Filed:

May. 14, 2018
Applicants:

Universidade DE Coimbra, Coimbra, PT;

Egas Moniz—cooperativa DE Ensino Superior, Crl, Caparica, PT;

Instituto DE Medicina Molecular, Lisbon, PT;

Inventors:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/431 (2006.01); A61P 31/18 (2006.01); A61P 33/06 (2006.01); C07D 513/04 (2006.01); C07D 513/20 (2006.01); A61K 31/395 (2006.01); A61K 31/43 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/431 (2013.01); A61K 31/395 (2013.01); A61K 31/43 (2013.01); A61K 45/06 (2013.01); A61P 31/18 (2018.01); A61P 33/06 (2018.01); C07D 513/04 (2013.01); C07D 513/20 (2013.01);
Abstract

The present disclosure relates to a new class of antimicrobial agents. In particular, this disclosure provides the identification and characterization of novel spiro-lactam compounds as anti-HIV/AIDS and anti-malarial agents. Furthermore, this disclosure also provides the preparation of spiro-β-penicillanic acids, which proved to be potent inhibitors of HIV.


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