The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 06, 2023
Filed:
Oct. 25, 2021
Applicant:
Cloudbreak Therapeutics, Llc, Irvine, CA (US);
Inventors:
Assignee:
Cloudbreak Therapeutics, LLC, Irvine, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/496 (2006.01); A61K 47/40 (2006.01); A61K 47/44 (2017.01); A61K 9/00 (2006.01); A61K 9/107 (2006.01); A61P 27/02 (2006.01);
U.S. Cl.
CPC ...
A61K 9/107 (2013.01); A61K 9/0048 (2013.01); A61K 31/496 (2013.01); A61K 47/40 (2013.01); A61K 47/44 (2013.01); A61P 27/02 (2018.01);
Abstract
Compositions comprising a therapeutically effective amount of a multikinase inhibitor, such as nintedanib or axitinib or pazopanib, are provided, wherein the composition is an emulsion, such as a nanoemulsion, with lipophilic carrier (e.g., castor oil), a polyoxyl oil (e.g., polyolyl-35 castor oil), optionally with a surfactant (e.g., polysorbate 80), optionally with a cyclic oligosaccharide, such as a cyclodextrin (e.g., 2-hydroxypropyl-beta-cyclodextrin), as a solubilizer. Methods for treating ocular conditions with the compositions are also provided.