The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 30, 2023

Filed:

Jun. 11, 2020
Applicant:

Life Technologies Corporation, Carlsbad, CA (US);

Inventors:

Yong Chu, Castro Valley, CA (US);

Stephanie Jo Schneider, Mountain View, CA (US);

Rylan Schaeffer, Mountain View, CA (US);

David Woo, Foster City, CA (US);

Assignee:

Life Technologies Corporation, Carlsbad, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G06K 9/62 (2022.01); G16B 30/00 (2019.01); G16B 40/00 (2019.01); G16B 25/00 (2019.01); C12Q 1/6869 (2018.01); G06N 3/084 (2023.01); G06N 5/046 (2023.01);
U.S. Cl.
CPC ...
G16B 30/00 (2019.02); C12Q 1/6869 (2013.01); G06K 9/6201 (2013.01); G06K 9/623 (2013.01); G06K 9/6256 (2013.01); G06K 9/6277 (2013.01); G06N 3/084 (2013.01); G06N 5/046 (2013.01); G16B 25/00 (2019.02); G16B 40/00 (2019.02);
Abstract

A method of automatically sequencing or basecalling one or more DNA (deoxyribonucleic acid) molecules of a biological sample is described. The method comprises using a capillary electrophoresis genetic analyzer to measure the biological sample to obtain at least one input trace comprising digital data corresponding to fluorescence values for a plurality of scans. Scan labelling probabilities for the plurality of scans are generated using a trained artificial neural network comprising a plurality of layers including convolutional layers. A basecall sequence comprising a plurality of basecalls for the one or more DNA molecules based on the scan labelling probabilities for the plurality of scans is determined.


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