The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 30, 2023
Filed:
Apr. 09, 2018
Applicant:
The Council of the Queensland Institute of Medical Research, Herston, AU;
Inventors:
Geoffrey R. Hill, Herston, AU;
Ping Zhang, Herston, AU;
Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/50 (2006.01); C07K 14/535 (2006.01); C07K 14/54 (2006.01); C07K 14/73 (2006.01); C12N 5/0783 (2010.01);
U.S. Cl.
CPC ...
G01N 33/505 (2013.01); C07K 14/535 (2013.01); C07K 14/5412 (2013.01); C07K 14/5428 (2013.01); C07K 14/5446 (2013.01); C07K 14/70514 (2013.01); C12N 5/0637 (2013.01);
Abstract
Disclosed are methods of identifying immunosuppressive T1 regulatory T cells, including in methods of diagnosing the presence of immune tolerance, methods of producing immunosuppressive regulatory T cells, and methods of eliciting immune tolerance in a subject. These methods include screening T cells to detect EomesIL-10T cells or expressing recombinant Eomes in T cell populations to generate immunosuppressive regulatory T cells.