The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 30, 2023
Filed:
Nov. 01, 2021
The Trustees of Dartmouth College, Hanover, NH (US);
University Health Network, Toronto, CA;
Keith D. Paulsen, Hanover, NH (US);
David W. Roberts, Lyme, NH (US);
Dennis Wirth, Hanover, NH (US);
Brian C. Wilson, Toronto, CA;
Mira Sibai, Toronto, CA;
THE TRUSTEES OF DARTMOUTH COLLEGE, Hanover, NH (US);
UNIVERSITY HEALTH NETWORK, Toronto, CA;
Abstract
A method and device for determining the depth and fluorophore concentration of a fluorophore concentration below the surface of an optically absorbing and scattering medium suitable for use in fluorescence-based surgical guidance such as in tumor resection is described. Long-wavelength stimulus light us used to obtain deep tissue penetration. Recovery of depth is performed by fitting measured modulation amplitudes for each spatial frequency to precomputed modulation amplitudes in a table of modulation amplitudes indexed by optical parameters and depth.