The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 30, 2023

Filed:

Jan. 21, 2020
Applicant:

Cellular Research, Inc., San Jose, CA (US);

Inventors:

Eleen Shum, San Jose, CA (US);

Katherine Lazaruk, San Jose, CA (US);

Dennis E. Prosen, San Jose, CA (US);

Devon Jensen, San Jose, CA (US);

David Rosenfeld, San Jose, CA (US);

Janice H. Lai, San Jose, CA (US);

James Ghadiali, San Jose, CA (US);

Christina Chang, San Jose, CA (US);

Assignee:

Becton, Dickinson and Company, Franklin Lakes, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6806 (2018.01); C12Q 1/6876 (2018.01); C12Q 1/6853 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6876 (2013.01); C12Q 1/6806 (2013.01); C12Q 1/6853 (2013.01); C12Q 2525/173 (2013.01); C12Q 2525/191 (2013.01); C12Q 2525/204 (2013.01); C12Q 2531/113 (2013.01); C12Q 2563/185 (2013.01);
Abstract

Disclosed herein include systems, methods, compositions, and kits for determining protein expression and gene expression simultaneously and for sample indexing. In some embodiments, an oligonucleotide associated with a cellular component-binding reagent (e.g., an antibody) comprises one or more of a unique molecular label sequence, a primer adapter, antibody-specific barcode sequence, an alignment sequence, and/or a poly(A) sequence. In some embodiments, the oligonucleotide is associated with the cellular component-binding reagent via a linker (e.g., 5AmMC12).


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