The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 30, 2023
Filed:
Dec. 17, 2017
Applicant:
The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Bethesda, MD (US);
Inventors:
Joel Schneider, Frederick, MD (US);
Scott Walsh, Olney, MD (US);
Stephen Miller, Rockville, MD (US);
Yuji Yamada, Frederick, MD (US);
Scott Durum, Frederick, MD (US);
Caroline Andrews, Frederick, MD (US);
Wenqing Li, Frederick, MD (US);
Julie Hixon, Hagerstown, MD (US);
Steven Tau, Manchester, NH (US);
Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 7/08 (2006.01); A61K 9/00 (2006.01); A61K 9/06 (2006.01); A61K 35/17 (2015.01); A61L 27/22 (2006.01); A61L 27/52 (2006.01); A61L 27/54 (2006.01); C07K 14/54 (2006.01); C07K 14/705 (2006.01); C12N 5/00 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 7/08 (2013.01); A61K 9/0019 (2013.01); A61K 9/06 (2013.01); A61K 35/17 (2013.01); A61L 27/227 (2013.01); A61L 27/52 (2013.01); A61L 27/54 (2013.01); C07K 14/5418 (2013.01); C07K 14/705 (2013.01); C12N 5/0018 (2013.01); C12N 5/0062 (2013.01); A61K 38/00 (2013.01); A61L 2400/06 (2013.01); C07K 2319/00 (2013.01); C07K 2319/33 (2013.01); C07K 2319/35 (2013.01); C12N 2501/999 (2013.01); C12N 2513/00 (2013.01);
Abstract
This disclosure provides novel anionic amphiphilic β-hairpin peptides that self-assemble under appropriate conditions to form a reversible gel-sol hydrogel that can be used, for example, to readily deliver protein therapeutics and cells by injection to a target location in a subject.