The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 30, 2023

Filed:

Dec. 18, 2020
Applicant:

Pfizer Inc., New York, NY (US);

Inventors:

Scott William Bagley, Mystic, CT (US);

Agustin Casimiro-Garcia, Concord, MA (US);

Xiayun Cheng, Old Saybrook, CT (US);

Jennifer Elizabeth Davoren, Cambridge, MA (US);

Rajiah Aldrin Denny, Sharon, MA (US);

Brian Stephen Gerstenberger, Cambridge, MA (US);

Frank Eldridge Lovering, Acton, MA (US);

Mihir Dineshkumar Parikh, East Greenwich, RI (US);

Joseph Walter Strohbach, Wentzville, MO (US);

John Isidro Trujillo, Ledyard, CT (US);

Assignee:

Pfizer Inc., New York, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/14 (2006.01); A61P 17/00 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 413/14 (2013.01); A61K 45/06 (2013.01); A61P 17/00 (2018.01);
Abstract

The invention relates to benzimidazoles of Formula (I) and pharmaceutically acceptable salts thereof, wherein Rto Rare as defined in the description; to their use in medicine; to compositions containing them; to processes for their preparation; and to intermediates used in such processes. The benzimidazoles of Formula (I) are ITK inhibitors and are therefore potentially useful in the treatment of a wide range of disorders including, atopic dermatitis.


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