The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 30, 2023
Filed:
Jun. 18, 2020
Revolution Medicines, Inc., Redwood City, CA (US);
Elena S. Koltun, Redwood City, CA (US);
Kevin Mellem, Redwood City, CA (US);
Adrian Gill, Redwood City, CA (US);
Gert Kiss, Redwood City, CA (US);
Christopher Semko, Redwood City, CA (US);
Naing Aay, Redwood City, CA (US);
Andreas Buckl, Redwood City, CA (US);
Ashutosh Jogalekar, Redwood City, CA (US);
Walter Won, Redwood City, CA (US);
REVOLUTION MEDICINES, INC., Redwood City, CA (US);
Abstract
The present disclosure is directed to inhibitors of SHP2, such as pyrazine compounds, and their use in the treatment of disease associated with SHP2 modulation, such as Noonan Syndrome, Leopard Syndrome, juvenile myelomonocytic leukemias, neuroblastoma, melanoma, acute myeloid leukemia and cancers of the breast, lung and colon. Also disclosed are pharmaceutical compositions comprising the same.