The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 30, 2023

Filed:

Jan. 21, 2021
Applicant:

Apotex Inc., Toronto, CA;

Inventors:

Fabio E. S. Souza, Brantford, CA;

Mohammed Abdul Raheem, Brantford, CA;

Yajun Zhao, Brantford, CA;

Siva Ramarao Kakani, Brantford, CA;

Minh T. N. Nguyen, Brantford, CA;

Alexander J. Stirk, Brantford, CA;

Allan W. Rey, Brantford, CA;

Stuart P. Green, Brantford, CA;

Assignee:

Apotex Inc., Toronto, CA;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C 217/48 (2006.01);
U.S. Cl.
CPC ...
C07C 217/48 (2013.01); C07B 2200/13 (2013.01);
Abstract

The present invention provides novel crystalline forms of zuclomiphene citrate. Specific crystalline forms provided by the present invention include zuclomiphene citrate Forms APO-I, APO-II, APO-III, and APO-IV. Also provided are pharmaceutical compositions including the zuclomiphene citrate crystalline forms, processes for the preparation thereof and the use of these forms in the treatment of a disorder selected from the group including osteoporosis, bone fractures, loss of bone mineral density (BMD) and hot flashes in a subject suffering therefrom.


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