The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 30, 2023

Filed:

Nov. 14, 2017
Applicant:

The Regents of the University of California, Oakland, CA (US);

Inventors:

R. Michael van Dam, Sherman Oaks, CA (US);

Noel S. Ha, Los Angeles, CA (US);

Jason Jones, Los Angeles, CA (US);

Jimmy Ly, San Francisco, CA (US);

Stephen Liu, Los Angeles, CA (US);

Shilin Cheung, North Hills, CA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
B01D 57/02 (2006.01); G01N 27/447 (2006.01); A61K 51/00 (2006.01); B01L 3/00 (2006.01);
U.S. Cl.
CPC ...
B01D 57/02 (2013.01); A61K 51/00 (2013.01); B01L 3/502715 (2013.01); B01L 3/502738 (2013.01); G01N 27/44717 (2013.01); G01N 27/44721 (2013.01); G01N 27/44743 (2013.01); G01N 27/44791 (2013.01);
Abstract

A microfluidic chip device for the purification of radiochemical compounds includes a chip having an injection channel and intersecting branch channels with a plurality of valves are located along the injection channel and branch channels and configured to retain a plug of solution containing the radiochemical compound. The chip further includes a serpentine channel segment (for separation) coupled to the output of the injection channel. A high voltage power source advances the plug of solution through the purification region and into the downstream fraction collection channel. The chip includes a downstream fraction collection channel coupled to the serpentine channel segment and having an optical and radiation detection regions. One or more branch fraction channels intersect with the fraction collection channel and include valves located therein so that the radiochemical compound that is detected using a radiation detector is directed into the desired branch fraction channel for subsequent use.


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