The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 30, 2023
Filed:
Sep. 28, 2018
Immpact-bio Ltd., Ness Ziona, IL;
Gavish-galilee Bio Applications Ltd., Kiryat Shmona, IL;
Gideon Gross, Moshav Almagor, IL;
Will Gibson, Boston, MA (US);
Dvir Dahary, Tel Aviv, IL;
Merav Beiman, Ness Ziona, IL;
ImmPACT-Bio Ltd., Ness Ziona, IL;
Gavish-Galilee Bio Applications Ltd., Kiryat Shmona, IL;
Abstract
The present invention provides a method of identifying a target for preparing an inhibitory chimeric antigen receptor (iCAR) or a protective chimeric antigen receptor (pCAR) capable of preventing or attenuating undesired activation of an effector immune cell. Also provided are a list of iCAR targets, as well as vectors and transduced effector immune cells comprising the nucleic acid molecule and methods for treatment of cancer comprising administering the transduced effector immune cells are further provided.