The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 30, 2023
Filed:
Oct. 23, 2018
Applicants:
Dompe' Farmaceutici S.p.a., Milan, IT;
Research Institute AT Nationwide Children's Hospital, Columbus, OH (US);
Inventors:
Ryan David Roberts, Grove City, OH (US);
Laura Brandolini, L'Aquila, IT;
Assignees:
Dompe' Farmaceutici S.P.A., Milan, IT;
Research Institute at Nationwide Children's Hospital, Columbus, OH (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61P 35/00 (2006.01); A61K 31/18 (2006.01); C07C 311/03 (2006.01); C07C 311/08 (2006.01); A61K 31/426 (2006.01); A61K 33/243 (2019.01); A61K 31/475 (2006.01); A61K 31/519 (2006.01); A61K 31/675 (2006.01); A61K 31/704 (2006.01); A61K 31/7048 (2006.01); A61K 38/12 (2006.01);
U.S. Cl.
CPC ...
A61K 31/426 (2013.01); A61K 31/18 (2013.01); A61K 31/475 (2013.01); A61K 31/519 (2013.01); A61K 31/675 (2013.01); A61K 31/704 (2013.01); A61K 31/7048 (2013.01); A61K 33/243 (2019.01); A61K 38/12 (2013.01); A61P 35/00 (2018.01);
Abstract
The present invention relates to IL-8 inhibitor compounds, preferably dual CXCR1/CXCR2 receptor inhibitors, useful in the treatment and/or prevention of some sarcomas, preferably in the treatment and/or prevention of osteosarcoma, Ewing sarcoma, rhabdomyosarcoma or lung metastasis associated thereof.