The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 23, 2023
Filed:
Jun. 25, 2020
Applicant:
Eutropics Pharmaceuticals, Inc., Cambridge, MA (US);
Inventor:
Michael H. Cardone, Dorchester, MA (US);
Assignee:
Eutropics Pharmaceuticals, Inc., Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 31/00 (2006.01); G01N 33/53 (2006.01); G01N 33/574 (2006.01); C07K 16/40 (2006.01);
U.S. Cl.
CPC ...
G01N 33/57496 (2013.01); C07K 16/40 (2013.01); G01N 33/574 (2013.01); G01N 33/57488 (2013.01); C07K 2317/622 (2013.01); G01N 2333/96466 (2013.01); G01N 2800/52 (2013.01);
Abstract
The present invention relates to methods of determining cancer cell sensitivity to treatment by using antibodies to detect the presence of heterodimers in the cell, as well as to determine the relationship between the antibody binding to the heterodimer in the cancer cell and the sensitivity of the cell to cancer treatment. The invention also provides a method of predicting therapeutic efficacy in a cancer patient.