The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 23, 2023

Filed:

Dec. 16, 2019
Applicant:

Sphere Fluidics Limited, Cambridge, GB;

Inventors:

Clive Adrian Smith, Hertford, GB;

Xin Li, Cambridge, GB;

Frank F. Craig, Cambridge, GB;

Assignee:

Sphere Fluidics Limited, Cambridge, GB;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 15/10 (2006.01); B01L 3/00 (2006.01); G01N 15/14 (2006.01); H01J 49/00 (2006.01); H01J 49/04 (2006.01);
U.S. Cl.
CPC ...
G01N 15/1031 (2013.01); B01L 3/50273 (2013.01); B01L 3/502715 (2013.01); B01L 3/502784 (2013.01); G01N 15/1056 (2013.01); G01N 15/1404 (2013.01); B01L 2200/0652 (2013.01); B01L 2300/0627 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0864 (2013.01); B01L 2400/0424 (2013.01); B01L 2400/0427 (2013.01); B01L 2400/084 (2013.01); G01N 2015/1081 (2013.01); G01N 2015/149 (2013.01); G01N 2015/1486 (2013.01); H01J 49/0031 (2013.01); H01J 49/04 (2013.01);
Abstract

A method for aligning sequences of droplets in streams of an emulsion comprising target droplets and tag droplets, a tag droplet comprising first and second tags. A target droplet is split into first and second target droplets and a tag droplet is split into first and second tag droplets. Each of the first and second tag droplets comprise the first and second tags. The first target droplet and first tag droplet are in a first stream of droplets, and the second target droplet and second tag droplet are in a second stream of droplets. The method detects the first tag droplets and first target droplets in the first stream and the second tag droplets and second target droplets in the second stream, determines a first sequence of droplets in the first stream and a second sequence of droplets in the second stream, and compares these to align the sequences.


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