The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 23, 2023
Filed:
May. 23, 2018
University of Florida Research Foundation, Inc., Gainesville, FL (US);
Rosemary Loria, Gainesville, FL (US);
Yucheng Zhang, Gainesville, FL (US);
Yousong Ding, Gainesville, FL (US);
Guangde Jiang, Gainesville, FL (US);
University of Florida Research Foundation, Incorporated, Gainesville, FL (US);
Abstract
The present disclosure includes genetically engineered, non-pathogenicbacterium with exogenous, non-native Thaxtomin A (ThxA) biosynthetic gene clusters conferring the genetically engineered, non-pathogenicbacterium with the ability to produce thaxtomin A. Also included are methods of providing thaxtomin producing capability in non-nativebacterial strains, methods of producing thaxtomin compounds with the genetically engineeredbacteria of the present disclosure, and methods of producing thaxtomin compounds and nitro-tryptophan analogs, and fluorinated thaxtomin compounds, analogs, and intermediates with the genetically engineeredbacteria of the present disclosure.