The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 23, 2023

Filed:

Dec. 31, 2018
Applicant:

Luxembourg Institute of Science and Technology (List), Esch-sur-Alzette, LU;

Inventors:

Arno Gutleb, Remich, LU;

Tommaso Serchi, Kirsch-les-Sierck, FR;

Mathieu Gerard, Rehon, FR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12M 1/42 (2006.01); C12M 1/00 (2006.01); C12M 1/34 (2006.01);
U.S. Cl.
CPC ...
C12M 35/04 (2013.01); C12M 29/14 (2013.01); C12M 41/14 (2013.01); C12M 41/40 (2013.01);
Abstract

A system for incubating one or more cells and/or organotypic cultures for biological investigation, in particular for toxicology assessment, comprising a bio-incubator and a pressure system fluidly connected with the bio-incubator. The pressure system is a cyclic gas pressure system configured for cyclically varying the gas pressure in the bio-incubator between a negative pressure and a positive pressure compared to the atmospheric pressure, so as to reproduce the pressure conditions in lungs of a living mammal. The system is remarkable in that the cyclic gas pressure system comprises a feedthrough with a pipe configured to deviate the air influx from the one or more cells and/or organotypic cultures.


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