The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 23, 2023

Filed:

Jun. 23, 2020
Applicant:

Ampsource Biopharma Shanghai Inc., Shanghai, CN;

Inventors:

Zhu Wang, Shanghai, CN;

Yongjuan Gao, Shanghai, CN;

Si Chen, Shanghai, CN;

Cecily Rou-Yun Sun, Shanghai, CN;

Yuncheng Zheng, Shanghai, CN;

Bill Nai-Chau Sun, Shanghai, CN;

Qiang Li, Shanghai, CN;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/22 (2006.01); A61K 38/18 (2006.01);
U.S. Cl.
CPC ...
C07K 16/22 (2013.01); A61K 38/185 (2013.01); C07K 2317/24 (2013.01); C07K 2317/565 (2013.01); C07K 2317/92 (2013.01);
Abstract

The invention provides an antibody and/or an antigen binding fragment that binds to NGF, and the amino acid sequences of the heavy chain and light chain variable regions of the antibody. The NGF antibody and/or its antigen binding fragment provided by the invention has high affinity for NGF and can effectively block the binding between NGF receptor and NGF. This antibody and/or its antigen binding fragment can inhibit the binding activity of NGF and its receptor in vitro, and is suitable for the treatment of pain diseases which are related to the haughty expression or increased expression of NGF.


Find Patent Forward Citations

Loading…