The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 23, 2023

Filed:

Jun. 16, 2020
Applicant:

Genentech, Inc., South San Francisco, CA (US);

Inventors:

Jack Alexander Terrett, South San Francisco, CA (US);

Huifen Chen, South San Francisco, CA (US);

Lea Constantineau-Forget, Montreal, CA;

Robin Larouche-Gauthier, Montreal, CA;

Luce Lépissier, Montreal, CA;

Francis Beaumier, Montreal, CA;

Martin Déry, Montreal, CA;

Chantal Grand-Maître, Montreal, CA;

Claudio Sturino, Montreal, CA;

Matthew Volgraf, South San Francisco, CA (US);

Elisia Villemure, South San Francisco, CA (US);

Assignee:

Genentech, Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/427 (2006.01); A61P 11/00 (2006.01); A61P 23/00 (2006.01); A61P 25/00 (2006.01); A61P 29/00 (2006.01); C07D 513/04 (2006.01); C07D 473/30 (2006.01); C07D 487/04 (2006.01); C07D 498/04 (2006.01); C07D 471/04 (2006.01); C07D 413/14 (2006.01);
U.S. Cl.
CPC ...
C07D 413/14 (2013.01); A61K 31/427 (2013.01); A61P 11/00 (2018.01); A61P 23/00 (2018.01); A61P 25/00 (2018.01); A61P 29/00 (2018.01); C07D 471/04 (2013.01); C07D 473/30 (2013.01); C07D 487/04 (2013.01); C07D 498/04 (2013.01); C07D 513/04 (2013.01);
Abstract

The invention relates to methods of using compounds formula I: and pharmaceutically acceptable salts thereof wherein A, X, R, Rand n are as defined herein. In addition, the present invention relates to methods of manufacturing and methods of using the compounds of formula I as well as pharmaceutical compositions containing such compounds. The compounds may be useful in treating diseases and conditions mediated by TRPA1, such as pain.


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