The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 23, 2023

Filed:

Oct. 12, 2022
Applicants:

Beijing Grand Johamu Pharmaceutical Company, Ltd., Beijing, CN;

Nanjing Gritpharmaco., Ltd., NanJing, CN;

Inventors:

Weiye Wei, Beijing, CN;

Jiannan Yang, Beijing, CN;

Xiaotao Wu, Beijing, CN;

Taotao Zhao, Beijing, CN;

Hao Wang, Beijing, CN;

Chao Li, Beijing, CN;

Lei Qu, Beijing, CN;

Bin Wang, Beijing, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/14 (2006.01); A61P 31/14 (2006.01); A61K 9/20 (2006.01);
U.S. Cl.
CPC ...
C07D 403/14 (2013.01); A61K 9/2009 (2013.01); A61K 9/2013 (2013.01); A61K 9/2054 (2013.01); A61K 9/2059 (2013.01); C07B 2200/13 (2013.01);
Abstract

The present disclosure provides a crystal form of a compound and fumaric acid, an active pharmaceutical ingredient and a pharmaceutical composition containing the same, and a method for treating coronavirus-induced diseases a using the same. In particular, the crystal form of the present disclosure comprises the compound of Formula (I) and fumaric acid, and the X-ray powder diffraction pattern of the crystal form obtained using Cu-Kα radiation includes at least three peaks selected from the group consisting of: 0.94°±0.2° 2θ, 19.06°±0.2° 2θ, 23.50°±0.2° 2θ, and 24.66°±0.2° 2θ. The crystal form of the present disclosure has a high purity, good stability, and a high melting point.


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