The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 23, 2023
Filed:
Jul. 12, 2018
Applicant:
Board of Supervisors of Louisiana State University and Agricultural and Mechanical College, Baton Rouge, LA (US);
Inventors:
Dennis J. Paul, New Orleans, LA (US);
Harry J. Gould, III, New Orleans, LA (US);
Assignee:
Board of Supervisors of Louisiana State University and Agricultural and Mechanical College, Baton Rouge, LA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61N 2/02 (2006.01); A61B 5/05 (2021.01); A61P 35/00 (2006.01); A61K 31/352 (2006.01); A61K 31/7048 (2006.01);
U.S. Cl.
CPC ...
A61N 2/02 (2013.01); A61B 5/05 (2013.01); A61K 31/352 (2013.01); A61K 31/7048 (2013.01); A61P 35/00 (2018.01);
Abstract
Methods are provided for targeting cancer cells that over-express voltage-gated sodium channels (VGSCs or 'sodium channels') and causing osmotic lysis of these cancer cells by initially inhibiting the sodium, potassium-adenosine triphosphatase (Na, K-ATPase or 'sodium pump'), and then stimulating the VGSCs by pulsed magnetic field gradients to cause sodium and water to enter the cancer cells.