The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 23, 2023
Filed:
Oct. 23, 2020
Applicant:
Bolt Biotherapeutics, Inc., Redwood City, CA (US);
Inventors:
Romas Kudirka, Redwood City, CA (US);
Brian Safina, Redwood City, CA (US);
Assignee:
BOLT BIOTHERAPEUTICS, INC., Redwood City, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/68 (2017.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
A61K 47/6889 (2017.08); A61K 47/6803 (2017.08); A61K 47/6849 (2017.08); C07K 16/2827 (2013.01);
Abstract
The invention provides immunoconjugates of Formula I comprising an antibody linked by conjugation to one or more thienoazepine derivatives. The invention also provides thienoazepine derivative intermediate compositions comprising a reactive functional group. Such intermediate compositions are suitable substrates for formation of the immunoconjugates through a linker or linking moiety. The invention further provides methods of treating cancer with the immunoconjugates.