The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 16, 2023

Filed:

Apr. 30, 2021
Applicant:

Lacrisciences, Llc, Washington, DC (US);

Inventors:

Paul T. Gavaris, Washington, DC (US);

Chris D. Geddes, Bel Air, MD (US);

Ali H. Ghovanlou, Potomac, MD (US);

Assignee:

LACRISCIENCES, LLC, Washington, DC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 21/552 (2014.01); G01N 33/48 (2006.01); A61B 3/10 (2006.01); G01N 33/84 (2006.01); A61B 5/1455 (2006.01);
U.S. Cl.
CPC ...
G01N 21/554 (2013.01); A61B 3/101 (2013.01); A61B 5/1455 (2013.01); G01N 21/553 (2013.01); G01N 33/84 (2013.01); G01N 2800/16 (2013.01);
Abstract

Systems and methods for determining the osmolarity of a sample are provided. Aspects of the subject methods include contacting a sensing surface of a surface plasmon resonance based sensor with a sample, and generating one or more data sets at at least two wavelengths over a time interval, wherein the data sets are used to determine the osmolarity of the sample. The subject methods find use in determining the osmolarity of a sample, such as a biological sample (e.g., a tear fluid), and in the diagnosis and/or monitoring of various diseases and disorders, such as, e.g., dry eye disease.


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