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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11649456 B1

PDFFull Text
Date of Patent:
May. 16, 2023

Filed:

Sep. 20, 2018

Functional nucleic acid molecule and use thereof

Applicants:

Fondazione Istituto Italiano Di Tecnologia, Genoa, IT;

Scuola Internazionale Superiore Di Studi Avanzati, Trieste, IT;

Inventors:

Stefano Gustincich, Genoa, IT;

Silvia Zucchelli, Genoa, IT;

Assignees:

FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA, Genoa, IT;

SCUOLA INTERNAZIONALE SUPERIORE DI STUDI AVANZATI, Trieste, IT;

Attorneys:

ALGM, LLP

Harry J. Guttman

Primary Examiner:

Kimberly Chong

Int. Cl.
CPC ...
C07H 21/04 (2006.01); C12N 15/113 (2010.01); C12N 15/67 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); C12N 15/67 (2013.01); A61K 48/00 (2013.01); C12N 2310/11 (2013.01); C12N 2310/3519 (2013.01); C12N 2840/105 (2013.01); C12N 2840/203 (2013.01);
Abstract

There is disclosed a trans-acting functional nucleic acid molecule comprising a eukaryotic target binding sequence comprising a sequence reverse complementary to a target mRNA sequence for which protein translation is to be enhanced, and a regulatory sequence comprising an internal ribosome entry site (IRES) sequence or an internal ribosome entry site (IRES) derived sequence and enhancing translation of the target mRNA sequence, wherein the regulatory sequence is located 3' of the target binding sequence.

Find Patent Forward Citations

Gustincich, Stefano. (2023). Functional nucleic acid molecule and use thereof (U.S. Patent No. 11649456). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11649456

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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