The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 16, 2023
Filed:
Apr. 01, 2019
University of Geneva, Geneva, CH;
Les Hôpitaux Universitaires DE Genève, Geneva, CH;
University of Zurich, Zurich, CH;
Karl-Heinz Krause, Geneva, CH;
Francis Rousset, Geneva, CH;
Patrick Salmon, Geneva, CH;
Marco Alessandrini, Geneva, CH;
Roberto Speck, Zurich, CH;
Simon Bredl, Zurich, CH;
Tafadzwa Mlambo, Zurich, CH;
Renier Myburgh, Zurich, CH;
UNIVERSITY OF GENEVA, Geneva, CH;
LES HÔPITAUX UNIVERSITAIRES DE GENÈVE, Geneva, CH;
UNIVERSITY OF ZURICH, Zurich, CH;
Abstract
The present disclosure relates to miRNA expression constructs, such as for expression of multiple miRNAs and use thereof to knockdown target gene expression. In some aspects, the expression constructs include a promoter element, a spacer sequence and a miRNA coding sequence. In some aspects, constructs provide enhanced immune cell function.