The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 16, 2023
Filed:
Dec. 13, 2018
Kirin Holdings Kabushiki Kaisha, Tokyo-to, JP;
The University of Tokyo, Tokyo-to, JP;
Toshikazu Tsuji, Nakano-ku, JP;
Kumiko Ikado, Nakano-ku, JP;
Seiichi Uchiyama, Bunkyo-ku, JP;
Kyoko Kawamoto, Bunkyo-ku, JP;
KIRIN HOLDINGS KABUSHIKI KAISHA, Tokyo, JP;
THE UNIVERSITY OF TOKYO, Tokyo, JP;
Abstract
There is provided a method for introducing a temperature-sensitive probe comprising a copolymer, which comprises a thermoresponsive unit and a fluorescent unit, into a cell, and the method using the copolymer further comprising a cationic unit as the temperature-sensitive probe, and the method comprising the step of mixing the copolymer with the cell in a solvent. The copolymer can be preferably used as a fluorescence temperature sensor which measures intracellular temperature since the copolymer has a cationic group and thus enters into a cell without using a special method.