The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 16, 2023
Filed:
Feb. 06, 2018
Applicant:
Seattle Children's Hospital, Seattle, WA (US);
Inventors:
Michael C. Jensen, Bainbridge Island, WA (US);
James Matthaei, Seattle, WA (US);
Assignee:
Seattle Children's Hospital, Seattle, WA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 47/54 (2017.01); A61K 49/00 (2006.01); C07K 16/28 (2006.01); C07K 16/08 (2006.01); C07K 16/12 (2006.01); C07K 16/30 (2006.01); C07K 16/32 (2006.01); A61P 35/00 (2006.01); G01N 33/569 (2006.01); A61K 39/00 (2006.01); C07K 14/725 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2809 (2013.01); A61K 47/544 (2017.08); A61P 35/00 (2018.01); C07K 16/08 (2013.01); C07K 16/12 (2013.01); C07K 16/30 (2013.01); C07K 16/32 (2013.01); A61K 49/0052 (2013.01); A61K 2039/5158 (2013.01); C07K 14/7051 (2013.01); C07K 2317/622 (2013.01); C07K 2319/03 (2013.01); C07K 2319/33 (2013.01);
Abstract
Aspects of the invention described herein relate to synthetic compounds that are useful for targeting and labeling tumor cells so as to facilitate recognition by binding agents including Chimeric Antigen Receptor T cells (CAR T cells), which are administered to a subject by intravenous or locoregional administration. Several compositions and methods of making and using these compositions to treat or inhibit a disease in a subject are contemplated.