The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 16, 2023
Filed:
Sep. 19, 2018
Applicant:
Kura Oncology, Inc., San Diego, CA (US);
Inventors:
Assignee:
KURA ONCOLOGY, INC., San Diego, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 495/04 (2006.01); A61K 31/519 (2006.01); C07D 519/00 (2006.01); A61P 35/00 (2006.01); C07D 471/10 (2006.01); C07D 487/04 (2006.01); C07D 487/10 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
C07D 519/00 (2013.01); A61P 35/00 (2018.01); C07D 471/10 (2013.01); C07D 487/04 (2013.01); C07D 487/10 (2013.01); A61K 9/0019 (2013.01); A61K 9/0053 (2013.01);
Abstract
The present disclosure provides methods of inhibiting the interaction of menin with MLL1, MLL2 and MLL-fusion oncoproteins. The methods are useful for the treatment of leukemia, solid cancers, diabetes and other diseases dependent on activity of MLL1, MLL2, MLL fusion proteins, and/or menin. Compositions for use in these methods are also provided.