The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 16, 2023
Filed:
Aug. 31, 2018
Optikira Llc, Cleveland, OH (US);
The Regents of the University of California, Oakland, CA (US);
Richard M. Keenan, Malvern, PA (US);
Bradley J. Backes, San Francisco, CA (US);
Dustin J. Maly, Seattle, WA (US);
Charles Reynolds, Malvern, PA (US);
Ben Whittaker, Malvern, PA (US);
Jamie Knight, Malvern, PA (US);
Jonathan Mark Sutton, Malvern, PA (US);
George Hynd, Malvern, PA (US);
Feroz R. Papa, Oakland, CA (US);
Scott A. Oakes, Oakland, CA (US);
Optikira LLC, Cleveland, OH (US);
The Regents of the University of California, Oakland, CA (US);
Abstract
Provided herein, inter alia, are substituted imidazo[1,5-α]pyrazine compounds, compositions and methods for treating or preventing an IRE1α-related disease or disorder. In certain embodiments, the disease or disorder is selected from the group consisting of a neurodegenerative disease, a demyelinating disease, cancer, an eye disease, a fibrotic disease, and diabetes.