The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 16, 2023

Filed:

Jul. 08, 2022
Applicant:

Sophrosyne Pharmaceuticals Limited, George Town, KY (US);

Inventors:

Lewis Feldberg, Montclair, NJ (US);

Akram Sabouni, Cary, NC (US);

Thomas R. Bailey, Phoenixville, PA (US);

Vincent Wing-Fai Tai, Cary, NC (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 211/46 (2006.01); A61P 25/32 (2006.01); C07C 333/20 (2006.01); C07C 333/04 (2006.01);
U.S. Cl.
CPC ...
C07D 211/46 (2013.01); A61P 25/32 (2018.01); C07C 333/04 (2013.01); C07C 333/20 (2013.01);
Abstract

The disclosure is directed to, in part, compounds, or pharmaceutically acceptable salts or solvates thereof, for modulating the activity of aldehyde dehydrogenase such as ALDH2 and/or methods for treating and/or preventing an alcohol related disorder such as alcohol use disorder, alcohol induced disorder, alcohol abuse, alcohol dependence, alcohol intoxication, alcohol withdrawal, and the like and/or methods for reducing the amount of alcohol consumed, reducing alcoholic cravings, or increasing the percentage of no heavy drinking days for a subject with alcohol use disorder.


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