The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 16, 2023
Filed:
Mar. 23, 2020
Applicant:
Genentech, Inc., South San Francisco, CA (US);
Inventors:
Thomas Pillow, San Francisco, CA (US);
Andrew G. Polson, San Francisco, CA (US);
Bing Zheng, Mountain View, CA (US);
Assignee:
Genentech, Inc., South San Francisco, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/357 (2006.01); A61K 45/06 (2006.01); C07D 407/12 (2006.01); C07K 19/00 (2006.01); G01N 33/567 (2006.01); A61K 47/54 (2017.01); A61K 47/68 (2017.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/541 (2017.08); A61K 31/357 (2013.01); A61K 45/06 (2013.01); A61K 47/6803 (2017.08); A61K 47/6849 (2017.08); A61K 47/6855 (2017.08); C07D 407/12 (2013.01); C07K 19/00 (2013.01); G01N 33/567 (2013.01); A61K 2039/572 (2013.01); A61K 2039/627 (2013.01);
Abstract
The invention relates generally to a silvestrol molecule activated with a leaving group. The invention further relates generally to an antibody-drug conjugate comprising an antibody conjugated by a linker to one or more silvestrol drug moieties and methods of treatment.