The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 16, 2023

Filed:

Jun. 21, 2021
Applicants:

Fred Hutchinson Cancer Center, Seattle, WA (US);

Blaze Bioscience, Inc., Seattle, WA (US);

Inventors:

James Olson, Seattle, WA (US);

Andrew David Strand, Seattle, WA (US);

Emily June Girard, Renton, WA (US);

Roland Strong, Seattle, WA (US);

Christopher Mehlin, Seattle, WA (US);

Colin Correnti, Seattle, WA (US);

Natalie Nairn, Seattle, WA (US);

Assignees:

FRED HUTCHINSON CANCER CENTER, Seattle, WA (US);

BLAZE BIOSCIENCE, INC., Seattle, WA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/17 (2006.01); C07K 14/435 (2006.01); A61K 47/64 (2017.01); A61K 47/66 (2017.01); A61P 19/02 (2006.01); A61K 49/00 (2006.01); A61K 51/08 (2006.01); A61K 47/65 (2017.01); A61P 19/04 (2006.01);
U.S. Cl.
CPC ...
A61K 38/17 (2013.01); A61K 47/64 (2017.08); A61K 47/65 (2017.08); A61K 47/66 (2017.08); A61K 49/0032 (2013.01); A61K 49/0056 (2013.01); A61K 51/08 (2013.01); A61P 19/02 (2018.01); A61P 19/04 (2018.01); C07K 14/435 (2013.01);
Abstract

Peptides that home, target, migrate to, are directed to, are retained by, or accumulate in and/or binds to the cartilage of a subject are disclosed. Pharmaceutical compositions and uses for peptides or peptide-active agent complexes comprising such peptides are also disclosed. Such compositions can be formulated for targeted delivery of a drug to a target region, tissue, structure or cell in the cartilage. Targeted compositions of the disclosure can deliver peptide or peptide-active agent complexes to target regions, tissues, structures or cells targeted by the peptide.


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