logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11648260 B1

PDFFull Text
Date of Patent:
May. 16, 2023

Filed:

Mar. 27, 2019

Vesicles comprising a pten inhibitor and uses of same

Applicants:

Technion Research and Development Foundation Limited, Haifa, IL;

Ramot AT Tel-aviv University Ltd., Tel Aviv, IL;

Inventors:

Shulamit Levenberg, Moreshet, IL;

Shaowei Guo, Haifa, IL;

Daniel Offen, Tel Aviv, IL;

Nisim Perets, Tel Aviv, IL;

Assignees:

TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITTED, Haifa, IL;

RAMOT AT TEL-AVIV UNIVERSITY LTD., Tel Aviv, IL;

Attorney:

Raphael Bellum PLLC

Primary Examiner:

Amy H Bowman

Int. Cl.
CPC ...
C07H 21/02 (2006.01); C07H 21/04 (2006.01); A61K 31/713 (2006.01); A61K 35/28 (2015.01); A61K 38/51 (2006.01); C12N 15/113 (2010.01); A61K 9/50 (2006.01); C12N 15/11 (2006.01); A61K 9/127 (2006.01);
U.S. Cl.
CPC ...
A61K 31/713 (2013.01); A61K 9/5068 (2013.01); A61K 35/28 (2013.01); A61K 38/51 (2013.01); C12N 15/111 (2013.01); C12N 15/113 (2013.01); C12N 15/1137 (2013.01); A61K 9/127 (2013.01); C12N 2310/14 (2013.01); C12N 2310/3515 (2013.01); C12N 2310/531 (2013.01); C12N 2320/32 (2013.01);
Abstract

The present invention provides pharmaceutical compositions comprising membrane vesicles, including extracellular vesicles including those referred to as exosomes, loaded with an exogenous Phosphatase and tensin homolog (PTEN) inhibitor. Methods of treating neurological diseases, disorders or conditions using the extracellular vesicles are provided. Isolated extracellular vesicles loaded with an exogenous Phosphatase and tensin homolog (PTEN) inhibitor are provided as well.

Find Patent Forward Citations

Loading…