The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 16, 2023

Filed:

Sep. 25, 2018
Applicant:

Tdeltas Limited, Thame, GB;

Inventors:

Kieran Clarke, Oxford, GB;

Brianna Stubbs, Oxford, GB;

Assignee:

TDELTAS LIMITED, Thame, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/22 (2006.01); A61P 3/04 (2006.01); A61K 31/70 (2006.01); A61K 45/06 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/22 (2013.01); A61K 31/70 (2013.01); A61P 3/04 (2018.01); A61K 9/0095 (2013.01); A61K 45/06 (2013.01); A61K 2800/92 (2013.01);
Abstract

The present invention provides a method of suppressing hunger by lowering plasma ghrelin levels comprising administration of a compound to a human or animal body, wherein the compound is selected from: (i) (R)-3-hydroxybutyrate; (ii) an ester of (R)-3-hydroxybutyrate; and (iii) an oligomer of (R)-3-hydroxybutyrate moieties; or a pharmaceutically acceptable salt or solvate thereof. The invention also provides a method of administering such a compound in a dosage effective to reduce hunger in order that a cosmetically beneficial loss or maintenance of body weight occurs, wherein in the method, plasma ghrelin levels are lowered. The aforementioned compound is also provided for use in a method of treatment of the human or animal body wherein the compound is administered and hunger is suppressed by lowering of plasma ghrelin levels. The compound is particularly useful for subjects having conditions associated with overeating, such as overweight, obese, severely obese patients or diabetic patients.


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